CHIT1 monoclonal antibody, clone 1D9G2
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More Files
- More Functions
Western Blot
Western blot analysis using CHIT1 monoclonal antibody, clone 1D9G2 (Cat # MAB10472) against truncated Trx-CHIT1 recombinant protein (1) and truncated CHIT1 (aa22-466)-hIgGFc transfected CHO-K1 cell lysate (2).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant CHIT1.
Immunogen
Recombinant protein corresponding to human CHIT1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:500-1:2000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascitic (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis using CHIT1 monoclonal antibody, clone 1D9G2 (Cat # MAB10472) against truncated Trx-CHIT1 recombinant protein (1) and truncated CHIT1 (aa22-466)-hIgGFc transfected CHO-K1 cell lysate (2).Enzyme-linked Immunoabsorbent Assay
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Gene Info — CHIT1
Entrez GeneID
1118Gene Name
CHIT1
Gene Alias
CHI3, CHIT, FLJ00314, MGC125322
Gene Description
chitinase 1 (chitotriosidase)
Omim ID
600031Gene Ontology
HyperlinkGene Summary
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq
Other Designations
chitotriosidase|plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
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Interactome
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Pathway
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Disease
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