Immunohistochemical analysis of paraffin-embedded human normal prostate tissue (A) and prostate adenocarcinoma tissue (B), showing cytoplasmic localization using AMACR monoclonal antibody, clone 2A10F3 (Cat # MAB10444) with DAB staining.
Confocal immunofluorescence analysis of LNCaP cells using AMACR monoclonal antibody, clone 2A10F3 (Cat # MAB10444) (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Alpha-methylacyl-CoA racemase is responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers, which are the only stereoisomers that can be degraded via peroxisomal beta-oxidation.[supplied by OMIM