NTRK1 monoclonal antibody, clone 6B2
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis using NTRK1 monoclonal antibody, clone 6B2 (Cat # MAB10431) against extracellular domain of human NTRK1 (aa 33-423).
Immunofluorescence
Confocal immunofluorescence analysis of PC-12 cells using NTRK1 monoclonal antibody, clone 6B2 (Cat # MAB10431) (green), showing membrane and cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant NTRK1.
Immunogen
Recombinant protein corresponding to human NTRK1.
Host
Mouse
Theoretical MW (kDa)
87.4
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:500-1:2000)
Immunofluorescence (1:200-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascitic (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using NTRK1 monoclonal antibody, clone 6B2 (Cat # MAB10431) against extracellular domain of human NTRK1 (aa 33-423).Immunofluorescence
Confocal immunofluorescence analysis of PC-12 cells using NTRK1 monoclonal antibody, clone 6B2 (Cat # MAB10431) (green), showing membrane and cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NTRK1
Entrez GeneID
4914Gene Name
NTRK1
Gene Alias
DKFZp781I14186, MTC, TRK, TRK1, TRKA, p140-TrkA
Gene Description
neurotrophic tyrosine kinase, receptor, type 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
Other Designations
OTTHUMP00000038736|Oncogene TRK|high affinity nerve growth factor receptor|tyrosine kinase receptor A
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Interactome
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Pathway
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Disease
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