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NTRK1 monoclonal antibody, clone 6B2

  • Catalog # : MAB10431
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant NTRK1.
  • Immunogen:
  • Recombinant protein corresponding to human NTRK1.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 87.4
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    Immunofluorescence (1:200-1:1000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascitic (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis using NTRK1 monoclonal antibody, clone 6B2 (Cat # MAB10431) against extracellular domain of human NTRK1 (aa 33-423).
  • Immunofluorescence
  • Immunofluorescence
  • Confocal immunofluorescence analysis of PC-12 cells using NTRK1 monoclonal antibody, clone 6B2 (Cat # MAB10431) (green), showing membrane and cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye.
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4914
  • Gene Name:
  • NTRK1
  • Gene Alias:
  • DKFZp781I14186,MTC,TRK,TRK1,TRKA,p140-TrkA
  • Gene Description:
  • neurotrophic tyrosine kinase, receptor, type 1
  • Gene Summary:
  • This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000038736,Oncogene TRK,high affinity nerve growth factor receptor,tyrosine kinase receptor A
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