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ITGB2 monoclonal antibody, clone 10E12

  • Catalog # : MAB10423
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant ITGB2.
  • Immunogen:
  • Recombinant protein corresponding to human ITGB2.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 85
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunofluorescence (1:200-1:1000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascitic (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Confocal immunofluorescence analysis of HL-60 cells using ITGB2 monoclonal antibody, clone 10E12 (Cat # MAB10423) (green). Blue: DRAQ5 fluorescent DNA dye.
  • Immunofluorescence
  • Immunofluorescence
  • Confocal immunofluorescence analysis of BCBL-1 cells (A) and L1210 cells (B) using ITGB2 monoclonal antibody, clone 10E12 (Cat # MAB10423) (red). Blue: DRAQ5 fluorescent DNA dye.
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3689
  • Gene Name:
  • ITGB2
  • Gene Alias:
  • CD18,LAD,LCAMB,LFA-1,MAC-1,MF17,MFI7
  • Gene Description:
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
  • Gene Summary:
  • The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • CD18 subunit,OTTHUMP00000115278,OTTHUMP00000115279,OTTHUMP00000115281,OTTHUMP00000115282,beta 2 integrin subunit,cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor),complement receptor C3 beta-subunit,integrin beta 2,integrin bet
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