IL2 monoclonal antibody, clone 8D5
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant IL2.
Immunogen
Recombinant protein corresponding to human IL2.
Host
Mouse
Theoretical MW (kDa)
17.6
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis using IL2 monoclonal antibody, clone 8D5 (Cat # MAB10421) against full-length IL2 recombinant protein with Trx tag (1) and full-length IL2-hIgGFc transfected HEK293 cell lysate(2).Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL2
Entrez GeneID
3558Gene Name
IL2
Gene Alias
IL-2, TCGF, lymphokine
Gene Description
interleukin 2
Omim ID
147680Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq
Other Designations
T cell growth factor|aldesleukin|interleukin-2|involved in regulation of T-cell clonal expansion
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Interactome
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