SRC monoclonal antibody, clone 4F1E8
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More Files
- More Functions
Western Blot
Western blot analysis using SRC monoclonal antibody, clone 4F1E8 (Cat # MAB10411) against truncated SRC-His recombinant protein (1) and PMA treated THP-1 cell lysate (2).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant SRC.
Immunogen
Recombinant protein corresponding to amino acids 10-193 of human SRC.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis using SRC monoclonal antibody, clone 4F1E8 (Cat # MAB10411) against truncated SRC-His recombinant protein (1) and PMA treated THP-1 cell lysate (2).Enzyme-linked Immunoabsorbent Assay
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Gene Info — SRC
Entrez GeneID
6714Gene Name
SRC
Gene Alias
ASV, SRC1, c-SRC, p60-Src
Gene Description
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Omim ID
190090Gene Ontology
HyperlinkGene Summary
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000174476|OTTHUMP00000174477|proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1
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Interactome
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Pathway
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Disease
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