KAT5 monoclonal antibody, clone 3F9
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis using KAT5 monoclonal antobody, clone 3F9 (Cat # MAB10398) against truncated KAT5 recombinant protein.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human liver carcinoma (A), recturn carcinoma (B), normal medulla tissue (C) and normal interbrain tissue (D), showing nuclear localization using KAT5 monoclonal antobody, clone 3F9 (Cat # MAB10398) with DAB staining.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant KAT5.
Immunogen
Recombinant protein corresponding to human KAT5.
Host
Mouse
Theoretical MW (kDa)
60
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using KAT5 monoclonal antobody, clone 3F9 (Cat # MAB10398) against truncated KAT5 recombinant protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human liver carcinoma (A), recturn carcinoma (B), normal medulla tissue (C) and normal interbrain tissue (D), showing nuclear localization using KAT5 monoclonal antobody, clone 3F9 (Cat # MAB10398) with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KAT5
Entrez GeneID
10524Gene Name
KAT5
Gene Alias
ESA1, HTATIP, HTATIP1, PLIP, TIP, TIP60, cPLA2
Gene Description
K(lysine) acetyltransferase 5
Omim ID
601409Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
Other Designations
HIV-1 Tat interactive protein, 60kDa|K-acetyltransferase 5|Tat interacting protein, 60kDa|cPLA2 interacting protein
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Interactome
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Publication Reference
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FAM135B sustains the reservoir of Tip60-ATM assembly to promote DNA damage response.
Kai Zhang, Qingnan Wu, Wenzhong Liu, Yan Wang, Lianmei Zhao, Jie Chen, Haoyu Liu, Siqi Liu, Jinting Li, Weimin Zhang, Qimin Zhan.
Clinical and Translational Medicine 2022 Aug; 12(8):e945.
Application：Co-IP, IF, WB-Tr, Human, HEK293T, KYSE30, KYSE30-FAM135B, KYSE510, YES2 cells.
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FAM135B sustains the reservoir of Tip60-ATM assembly to promote DNA damage response.
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