RPS6KA1 monoclonal antibody, clone 10B1D7A9
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant RPS6KA1.
Immunogen
Recombinant protein corresponding to human RPS6KA1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using RPS6KA1 monoclonal antobody, clone 10B1D7A9 (Cat # MAB10388) against truncated RPS6KA1 recombinant protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human small intestine tissue uing RPS6KA1 monoclonal antobody, clone 10B1D7A9 (Cat # MAB10388).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), colon adenocarcinoma (B), liver carcinoma (C), skin carcinoma (D), breast ductal tumor (E) and brain tumor (F), showing nuclear localization using RPS6KA1 monoclonal antobody, clone 10B1D7A9 (Cat # MAB10388) with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RPS6KA1
Entrez GeneID
6195Gene Name
RPS6KA1
Gene Alias
HU-1, MAPKAPK1A, RSK, RSK1
Gene Description
ribosomal protein S6 kinase, 90kDa, polypeptide 1
Omim ID
601684Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000004113|S6K-alpha 1|dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1)|p90-RSK 1|ribosomal protein S6 kinase alpha 1|ribosomal protein S6 kinase, 90kD, 1|ribosomal protein S6 kinase, 90kD, polypeptide 1
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Interactome
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Disease
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