NCOR1 monoclonal antibody, clone 7A7A9
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant NCOR1.
Immunogen
Recombinant protein corresponding to amino acids 1-192 of human NCOR1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using NCOR1 monoclonal antibody, clone 7A7A9 (Cat # MAB10376) against recombinant human NCOR1 protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human cerebra (A) and breast carcinoma tissue (B), showing nuclear location. using NCOR1 monoclonal antibody, clone 7A7A9 (Cat # MAB10376) with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NCOR1
Entrez GeneID
9611Gene Name
NCOR1
Gene Alias
KIAA1047, MGC104216, N-CoR, TRAC1, hCIT529I10, hN-CoR
Gene Description
nuclear receptor co-repressor 1
Omim ID
600849Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. [provided by RefSeq
Other Designations
thyroid hormone- and retinoic acid receptor-associated corepressor 1
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Interactome
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Disease
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