UBA7 monoclonal antibody, clone 5B10
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis using UBA7 monoclonal antobody, clone 5B10 (Cat # MAB10343) against Raji (1) and THP-1 (2) cell lysate.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant UBA7.
Immunogen
Recombinant protein corresponding to human UBA7.
Host
Mouse
Theoretical MW (kDa)
112
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis using UBA7 monoclonal antobody, clone 5B10 (Cat # MAB10343) against Raji (1) and THP-1 (2) cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — UBA7
Entrez GeneID
7318Gene Name
UBA7
Gene Alias
D8, MGC12713, UBA1B, UBE1L, UBE2
Gene Description
ubiquitin-like modifier activating enzyme 7
Omim ID
191325Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq
Other Designations
UBA1, ubiquitin-activating enzyme E1 homolog B|UBA7, ubiquitin-activating enzyme E1|ubiquitin-activating enzyme E1-like|ubiquitin-activating enzyme E1-related protein|ubiquitin-activating enzyme-2
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Interactome
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Pathway
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Disease
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