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Last updated: 2017/3/26
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TNFRSF11B monoclonal antibody, clone 5G2

  • Catalog # : MAB10335
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant TNFRSF11B.
  • Immunogen:
  • Recombinant protein corresponding to human TNFRSF11B.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 60
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunofluorescence (1:200-1:1000)
    Flow cytometry (1:200-1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis using TNFRSF11B monoclonal antobody, clone 5G2 (Cat # MAB10335) against HEK293 (1) and TNFRSF11B-hIgGFc transfected HEK293 (2) cell lysate.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of HL-60 cells using TNFRSF11B monoclonal antobody, clone 5G2 (Cat # MAB10335) (green). Blue: DRAQ5 fluorescent DNA dye.
  • ELISA
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HL-60 cells using TNFRSF11B monoclonal antobody, clone 5G2 (Cat # MAB10335) (green) and negative control (purple).
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4982
  • Gene Name:
  • TNFRSF11B
  • Gene Alias:
  • MGC29565,OCIF,OPG,TR1
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 11b
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • osteoclastogenesis inhibitory factor,osteoprotegerin
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