STK11 monoclonal antibody, clone 4H12
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant STK11.
Immunogen
Recombinant protein corresponding to human STK11.
Host
Mouse
Theoretical MW (kDa)
54
Reactivity
Human, Monkey, Mouse
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis using STK11 monoclonal antobody, clone 4H12 (Cat # MAB10327) against NIH/3T3 (1),Raw246.7 (2), COS-7 (3), Jurkat (4), HEK293 (5) and A-431 (6) cell lysate.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Flow cytometric analysis of K-562 cells using STK11 monoclonal antobody, clone 4H12 (Cat # MAB10327) (green) and negative control (purple). -
Gene Info — STK11
Entrez GeneID
6794Gene Name
STK11
Gene Alias
LKB1, PJS
Gene Description
serine/threonine kinase 11
Gene Ontology
HyperlinkGene Summary
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq
Other Designations
polarization-related protein LKB1|serine/threonine protein kinase 11
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