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PTH1R monoclonal antibody, clone 4D2

  • Catalog # : MAB10307
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant PTH1R.
  • Immunogen:
  • Recombinant protein corresponding to human PTH1R.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 66
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    Immunofluorescence (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis using PTH1R monoclonal antobody, clone 4D2 (Cat # MAB10307) against PTH1R-hIgGFc transfected HEK293 cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human kidney tissue using PTH1R monoclonal antobody, clone 4D2 (Cat # MAB10307) with DAB staining.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of SK-BR-3 cells using PTH1R monoclonal antobody, clone 4D2 (Cat # MAB10307) (green). Blue: DRAQ5 fluorescent DNA dye.
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5745
  • Gene Name:
  • PTH1R
  • Gene Alias:
  • MGC138426,MGC138452,PTHR,PTHR1
  • Gene Description:
  • parathyroid hormone 1 receptor
  • Gene Summary:
  • The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. [provided by RefSeq
  • Other Designations:
  • PTH/PTHr receptor,PTH/PTHrP type I receptor,parathyroid hormone receptor 1,parathyroid hormone/parathyroid hormone-related peptide receptor,parathyroid hormone/parathyroid hormone-related protein receptor,seven transmembrane helix receptor
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