IgG2a Z-mAb™ isotype control (aglycosylated) is a recombinant antibody with specific point mutations introduced to the CDRs (complementarity determining regions) of the mouse OKT3 antibody in order to knock out its binding to human CD3. It is aglycosylated in Fc region.
Protein A purification followed by size-exclusion chromatography purification
In PBS, pH 7.2
Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
This antibody is CDR-silenced and does not bind human CD3, the antigen of the parental antibody (OKT3).