IgG2a Z-mAb™ isotype control is a recombinant antibody with specific point mutations introduced to the CDRs (complementarity determining regions) of the mouse OKT3 antibody in order to knock out its binding to human CD3.
Protein A purification followed by size-exclusion chromatography purification
In PBS, pH 7.2
Store at -20°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
This antibody is CDR-silenced and does not bind human CD3, the antigen of the parental antibody (OKT3).