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Last updated: 2016/12/4
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CD180 monoclonal antibody, clone G28-8 (PE)

  • Catalog # : MAB10239
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against of CD180.
  • Immunogen:
  • Human tonsillar B cells.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 95-105
  • Reactivity:
  • Human
  • Specificity:
  • CD180, a TLR-like glycoprotein expressed on peripheral blood monocytes and dendritic cells, mantle zone B cells and marginal zone B cells, but very weakly on germinal center B cells.
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Purification:
  • Size-exclusion chromatography purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunoprecipitation
  • Functional Study
  • Flow Cytometry
  • Application Image
  • Immunoprecipitation
  • Functional Study
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4064
  • Gene Name:
  • CD180
  • Gene Alias:
  • LY64,Ly78,MGC126233,MGC126234,RP105
  • Gene Description:
  • CD180 molecule
  • Gene Summary:
  • CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq
  • Other Designations:
  • CD180 antigen,lymphocyte antigen-64, radioprotective, 105kDa
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