CD180 monoclonal antibody, clone G28-8
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Specification
Product Description
Mouse monoclonal antibody raised against CD180.
Immunogen
Human tonsillar B cells.
Host
Mouse
Theoretical MW (kDa)
95-105
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunoprecipitation
Functional Study
Flow Cytometry
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Gene Info — CD180
Entrez GeneID
4064Gene Name
CD180
Gene Alias
LY64, Ly78, MGC126233, MGC126234, RP105
Gene Description
CD180 molecule
Omim ID
602226Gene Ontology
HyperlinkGene Summary
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq
Other Designations
CD180 antigen|lymphocyte antigen-64, radioprotective, 105kDa
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Interactome
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Disease
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