SELP monoclonal antibody, clone AK4
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Specification
Product Description
Mouse monoclonal antibody raised against SELP.
Immunogen
Human platelets.
Host
Mouse
Theoretical MW (kDa)
140
Reactivity
Human, Non-Human Primates
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (1.5 ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunocytochemistry
Immunoprecipitation
Functional Study
Flow Cytometry
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Gene Info — SELP
Entrez GeneID
6403Gene Name
SELP
Gene Alias
CD62, CD62P, FLJ45155, GMP140, GRMP, LECAM3, PADGEM, PSEL
Gene Description
selectin P (granule membrane protein 140kDa, antigen CD62)
Gene Ontology
HyperlinkGene Summary
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq
Other Designations
OTTHUMP00000032609|antigen CD62|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet alpha-granule membrane protein|selectin P|selectin P (granule membrane protein 140kD, antigen CD62)
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Interactome
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Pathway
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Disease
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