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VCL monoclonal antibody, clone SP117

  • Catalog # : MAB10059
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of VCL.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human VCL.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 139
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded human heart sections with VCL monoclonal antibody, clone SP117 (Cat # MAB10059).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 7414
  • Gene Name:
  • VCL
  • Gene Alias:
  • CMD1W,MVCL
  • Gene Description:
  • vinculin
  • Gene Summary:
  • Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019861,OTTHUMP00000043885,metavinculin
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