Western blot analysis of mouse eye tissue extracts (60 ug) with CRABP2 monoclonal antibody, clone AT2E11 (Cat # MAB10007) at 1:250 dilution. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein. [provided by RefSeq
OTTHUMP00000038730,OTTHUMP00000038732,cellular retinoic acid-binding protein 2