Immunofluorescence staining of microtubular networks in NIH/3T3 mouse fibroblasts. A : Metaphase. B : Anaphase. C : Telophase. Gamma - tubulin (red) stained with TUBG1 monoclonal antibody, clone TU - 30 (Cat # MAB0975), alpha - tubulin (green) with polyclonal anti - alpha - tubulin antibody and nuclei with DAPI (blue).
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq