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Last updated: 2016/12/4
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ICAM3 monoclonal antibody, clone MEM-04

  • Catalog # : MAB0972
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ICAM3.
  • Immunogen:
  • Native purified ICAM3 from leukocytes of a patient suffering from a LGL-type leukemia.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 120-130
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with CD50 (ICAM-3), a 120-130 KDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes.
    The MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1).
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3385
  • Gene Name:
  • ICAM3
  • Gene Alias:
  • CD50,CDW50,ICAM-R
  • Gene Description:
  • intercellular adhesion molecule 3
  • Gene Summary:
  • The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq
  • Other Designations:
  • intercellular adhesion molecule-3
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