Subcellular localization of LAT2 by confocal microscopy in THP-1 human acute monocytic leukemia cell line. THP-1 cells were permeabilized and immunostained using LAT2 monoclonal antibody, clone NAP-07 (Cat # MAB0946 ; green). Nuclei are vizualized by propidium iodide (red).
This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq
OTTHUMP00000160648,OTTHUMP00000179118,OTTHUMP00000179119,Williams-Beuren syndrome chromosome region 15,Williams-Beuren syndrome chromosome region 5,linker for activation of B cells,linker for activation of T cells family member 2,non-T cell activation lin