Mouse monoclonal antibody raised against synthetic peptide of PAG1.
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PAG1.
Theoretical MW (kDa):
Bovine, Human, Mouse, Rat
This antibody recognizes an epitope located in the C-terminal domain of Csk-binding protein (Cbp / PAG), a 46 KDa ubiquitously expressed transmembrane adaptor protein present in membrane rafts (glycosphingolipid-enriched microdomains), which however migrates on SDS PAGE gels anomalously as an 80 KDa molecule.
The optimal working dilution should be determined by the end user.
In PBS, pH 7.4 (0.09% sodium azide)
Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Immunoprecipitation of human PAG1 from the lysate of Raji human Burkitt lymphoma cell line. Western blot was immunostained with human PAG1 monoclonal antibody, clone PAG - C1 (Cat # MAB0934). PAG1 is a 46 KDa adaptor protein, which however migrates on SDS PAGE gels anomalously as an 80 KDa molecule. Lane 1, 2 : Immunoprecipitation with PAG1 monoclonal antibody, clone PAG - C1 (Cat # MAB0934). Lane 3 : Immunoprecipitation with PAG1 polyclonal antibody.
The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation. [provided by RefSeq
Csk-binding protein,phosphoprotein associated with glycosphingolipid-enriched microdomains