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Last updated: 2017/6/25
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CD27 monoclonal antibody, clone LT27

  • Catalog # : MAB0923
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD27.
  • Immunogen:
  • Native purified CD27 from human peripheral blood lymphocytes.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 50-55
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with CD27 (T14), a 50-55 KDa type I transmembrane glycoprotein (member of the TNF-receptor superfamily) expressed on medullary thymocytes, peripheral T lymphocytes, some B lymphocytes and NK cells.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Surface staining of human peripheral blood cells with CD27 monoclonal antibody, clone LT27 (Cat # MAB0923) PE. Cells in the lymphocyte gate were used for analysis.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 939
  • Gene Name:
  • CD27
  • Gene Alias:
  • MGC20393,S152,T14,TNFRSF7,Tp55
  • Gene Description:
  • CD27 molecule
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq
  • Other Designations:
  • CD27 antigen,CD27L receptor,T cell activation antigen CD27,T cell antivation antigen S152,tumor necrosis factor receptor superfamily, member 7
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