GAPDHS monoclonal antibody, clone Hs-8
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Specification
Product Description
Mouse monoclonal antibody raised against native ACRV1.
Immunogen
Native purified human GAPDHS.
Host
Mouse
Reactivity
Human, Pig
Specificity
The antibody Hs-8 reacts with GAPDHS, the sperm-specific glyceraldehyde phosphate dehydrogenase, previously identified under the general name "intra-acrosomal protein".
Form
Liquid
Isotype
IgM
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunocytochemistry
Flow Cytometry
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Gene Info — GAPDHS
Entrez GeneID
26330Gene Name
GAPDHS
Gene Alias
GAPD2, GAPDH-2, GAPDS, HSD-35
Gene Description
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Omim ID
609169Gene Ontology
HyperlinkGene Summary
This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq
Other Designations
glyceraldehyde-3-phosphate dehydrogenase, testis-specific|spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2
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Interactome
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Disease
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Publication Reference
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Oxidation of glyceraldehyde-3-phosphate dehydrogenase decreases sperm motility in diabetes mellitus.
Liu J, Wang Y, Gong L, Sun C.
Biochemical and Biophysical Research Communications 2015 Sep; 465(2):245.
Application：IF, Human, Sperms.
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Oxidation of glyceraldehyde-3-phosphate dehydrogenase decreases sperm motility in diabetes mellitus.
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