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Last updated: 2017/1/15
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LCK monoclonal antibody, clone LCK-01

  • Catalog # : MAB0912
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of LCK.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to amino acids 22-36 of human LCK.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 56
  • Reactivity:
  • Human
  • Specificity:
  • This antibody LCK-01 recognizes defined epitope of Lck, a 56 KDa Src-family protein tyrosine kinase.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blotting analysis (reducing conditions) of human LCK in whole cell lysate using LCK monoclonal antibody, clone LCK - 01 (Cat # MAB0912) . Lane 1 : J. CaM - 1.6 cell line (a mutant derivate of the Jurkat cell line) transfected with LCK. Lane 2 : HEK 293T cell line transfected with LCK. Lane 3 : HEK 293T cell line (non - transfected) .
  • Immunocytochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunocytochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3932
  • Gene Name:
  • LCK
  • Gene Alias:
  • YT16,p56lck,pp58lck
  • Gene Description:
  • lymphocyte-specific protein tyrosine kinase
  • Gene Summary:
  • This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq
  • Other Designations:
  • T-lymphocyte specific protein tyrosine kinase p56lck,p56(LSTRA) protein-tyrosine kinase,protein tyrosine kinase,proto-oncogene tyrosine-protein kinase LCK
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