ICAM3 monoclonal antibody, clone MEM-171
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Specification
Product Description
Mouse monoclonal antibody raised against native ICAM3.
Immunogen
Native purified ICAM3 from human granulocytes.
Host
Mouse
Theoretical MW (kDa)
120-130
Reactivity
Human
Specificity
This antibody recognizes an epitope in the D2 domain of CD50 (ICAM-3), a 120-130 KDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunoprecipitation
Flow Cytometry
Surface staining of Jurkat human peripheral blood leukemia T cell line with ICAM3 monoclonal antibody, clone MEM - 171 (Cat # MAB0909) FITC. -
Gene Info — ICAM3
Entrez GeneID
3385Gene Name
ICAM3
Gene Alias
CD50, CDW50, ICAM-R
Gene Description
intercellular adhesion molecule 3
Omim ID
146631Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq
Other Designations
intercellular adhesion molecule-3
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Interactome
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Pathway
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