Western blotting analysis (non - reducing conditions) of whole cell lysate of various cell lines using B2M monoclonal antibody, clone B2M - 01 (Cat # MAB0899) . Lane 1 : Raji human Burkitt lymphoma cell line. Lane 2 : EL4 mouse lymphoblastic lymphoma cell line. Lane 3 : U 937 human histiocytic lymphoma cell line.
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia
beta chain of MHC class I molecules,beta-2-microglobin