CD48 monoclonal antibody, clone MEM-102
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Specification
Product Description
Mouse monoclonal antibody raised against native CD48.
Immunogen
Native purified CD48 from Raji human Burkitt's lymphoma cell line.
Host
Mouse
Theoretical MW (kDa)
40-47
Reactivity
Human, Primates
Specificity
This antibody reacts with CD48 antigen (Blast-1), a 40-47 KDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — CD48
Entrez GeneID
962Gene Name
CD48
Gene Alias
BCM1, BLAST, BLAST1, MEM-102, SLAMF2, hCD48, mCD48
Gene Description
CD48 molecule
Omim ID
109530Gene Ontology
HyperlinkGene Summary
BLAST1 is the designation used for an activation-associated cell surface glycoprotein of 40 to 45 kD expressed primarily in mitogen-stimulated human lymphocytes. The protein sequence predicted by the cDNA encoding BLAST1 indicates that BLAST1 is a member of the immunoglobulin supergene family. Yokoyama (1991) identified the BLAST1 activation/adhesion molecule as CD48.[supplied by OMIM
Other Designations
CD48 antigen (B-cell membrane protein)|OTTHUMP00000025680|OTTHUMP00000060268
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Interactome
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Pathway
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Disease
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Publication Reference
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Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization.
Baitsch L, Legat A, Barba L, Fuertes Marraco SA, Rivals JP, Baumgaertner P, Christiansen-Jucht C, Bouzourene H, Rimoldi D, Pircher H, Rufer N, Matter M, Michielin O, Speiser DE.
PLoS One 2012 Feb; 7(2):e30852.
Application：IHC-P, Human, Human melanoma.
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Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization.
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