Mouse monoclonal antibody raised against native ITGB1.
Native purified ITGB1 from leukocytes of a patient suffering from a LGL-type leukemia.
Theoretical MW (kDa):
Dog, Human, Pig
This antibody reacts with CD29 (integrin beta chain), a 130 KDa single chain type I glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits 1-6). CD29 is broadly expressed on majority of hematopoietic and non-hematopoietic cells (leukocytes, platelets, fibroblasts, endothelial cells, epithelial cells and mast cells).
The optimal working dilution should be determined by the end user.
In PBS, pH 7.4 (0.09% sodium azide)
Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Western blotting analysis (non - reducing conditions) of isolated peripheral blood lymphocytes of various species using ITGB1 monoclonal antibody, clone MEM - 101A (Cat # MAB0883) . Lane 1 : Lysate of human PBL. Lane 2 : Lysate of canine PBL. Lane 3 : Lysate of porcine PBL.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq