MS4A1 monoclonal antibody, clone MEM-97
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More Files
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Immunoprecipitation
Immunoprecipitation of human CD20 from the whole cell lysate of Raji human Burkitt lymphoma cell line. Western blot was immunostained with MS4A1 monoclonal antibody, clone MEM - 97 (Cat # MAB0881) . Lane 1 : Original lysate of Raji cells. Lane 2 : Immunoprecipitate by Isotypic mouse IgG1 control. Lane 3 : Original lysate of Raji cells. Lane 4 : Immunoprecipitate by anti - CD20 (MEM - 97) .
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Specification
Product Description
Mouse monoclonal antibody raised against native MS4A1.
Immunogen
Native purified MS4A1 from Raji human Burkitt's lymphoma cell line.
Host
Mouse
Theoretical MW (kDa)
33-37
Reactivity
Bovine, Human, Pig
Specificity
This antibody reacts with CD20 (Bp35), a 33-37 KDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunoprecipitation
Immunoprecipitation of human CD20 from the whole cell lysate of Raji human Burkitt lymphoma cell line. Western blot was immunostained with MS4A1 monoclonal antibody, clone MEM - 97 (Cat # MAB0881) . Lane 1 : Original lysate of Raji cells. Lane 2 : Immunoprecipitate by Isotypic mouse IgG1 control. Lane 3 : Original lysate of Raji cells. Lane 4 : Immunoprecipitate by anti - CD20 (MEM - 97) .Flow Cytometry
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Gene Info — MS4A1
Entrez GeneID
931Gene Name
MS4A1
Gene Alias
B1, Bp35, CD20, LEU-16, MGC3969, MS4A2, S7
Gene Description
membrane-spanning 4-domains, subfamily A, member 1
Omim ID
112210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq
Other Designations
B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor
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Interactome
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Pathway
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Disease
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