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Last updated: 2016/11/27
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MS4A1 monoclonal antibody, clone MEM-97

  • Catalog # : MAB0881
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native MS4A1.
  • Immunogen:
  • Native purified MS4A1 from Raji human Burkitt's lymphoma cell line.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 33-37
  • Reactivity:
  • Bovine, Human, Pig
  • Specificity:
  • This antibody reacts with CD20 (Bp35), a 33-37 KDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of human CD20 from the whole cell lysate of Raji human Burkitt lymphoma cell line. Western blot was immunostained with MS4A1 monoclonal antibody, clone MEM - 97 (Cat # MAB0881) . Lane 1 : Original lysate of Raji cells. Lane 2 : Immunoprecipitate by Isotypic mouse IgG1 control. Lane 3 : Original lysate of Raji cells. Lane 4 : Immunoprecipitate by anti - CD20 (MEM - 97) .
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 931
  • Gene Name:
  • MS4A1
  • Gene Alias:
  • B1,Bp35,CD20,LEU-16,MGC3969,MS4A2,S7
  • Gene Description:
  • membrane-spanning 4-domains, subfamily A, member 1
  • Gene Summary:
  • This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq
  • Other Designations:
  • B-lymphocyte cell-surface antigen B1,CD20 antigen,CD20 receptor
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