Mouse monoclonal antibody raised against native MS4A1.
Native purified MS4A1 from Raji human Burkitt's lymphoma cell line.
Theoretical MW (kDa):
Bovine, Human, Pig
This antibody reacts with CD20 (Bp35), a 33-37 KDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.
The optimal working dilution should be determined by the end user.
In PBS, pH 7.4 (0.09% sodium azide)
Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Immunoprecipitation of human CD20 from the whole cell lysate of Raji human Burkitt lymphoma cell line. Western blot was immunostained with MS4A1 monoclonal antibody, clone MEM - 97 (Cat # MAB0881) . Lane 1 : Original lysate of Raji cells. Lane 2 : Immunoprecipitate by Isotypic mouse IgG1 control. Lane 3 : Original lysate of Raji cells. Lane 4 : Immunoprecipitate by anti - CD20 (MEM - 97) .
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq