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Last updated: 2016/12/11
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CD3E monoclonal antibody, clone MEM-57

  • Catalog # : MAB0870
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD3E.
  • Immunogen:
  • Native purified CD3E from human thymocytes and T lymphocytes.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with gamma-epsilon and delta-epsilon dimers of human CD3 complex, a part of a bigger multisubunit T cell receptor complex (CD3/TCR) expressed on peripheral blood T lymphocytes and mature thymocytes.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunoprecipitation
  • Flow Cytometry
  • Flow Cytometry
  • Surface staining of human peripheral blood cells as Jurkat with CD3E monoclonal antibody, clone MEM - 57 (Cat # MAB0870) . Cells in the lymphocyte gate were used for analysis.
  • Application Image
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 916
  • Gene Name:
  • CD3E
  • Gene Alias:
  • FLJ18683,T3E,TCRE
  • Gene Description:
  • CD3e molecule, epsilon (CD3-TCR complex)
  • Gene Summary:
  • The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq
  • Other Designations:
  • CD3-epsilon,CD3E antigen, epsilon polypeptide,CD3e antigen, epsilon polypeptide (TiT3 complex),T-cell antigen receptor complex, epsilon subunit of T3,T-cell surface antigen T3/Leu-4 epsilon chain,T-cell surface glycoprotein CD3 epsilon chain
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