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Last updated: 2017/2/19
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KRT5/KRT18 monoclonal antibody, clone C-50

  • Catalog # : MAB0853
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native KRT5/KRT18.
  • Immunogen:
  • Cytoskeleton of human HeLa cell line.
  • Sequence:
  • RERMFNGEKINYT
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 58, 45
  • Reactivity:
  • Dog, Hamster, Human, Mouse, Rat, Sheep
  • Specificity:
  • This antibody reacts with Cytokeratin peptides 5 and 18 (58 and 45 KDa).
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blotting analysis of whole cell lysate of MCF-7 human breast adenocarcinoma cell line. Lane 1 : MW standard. Lane 2 : Immunostaining with KRT5 / KRT18 monoclonal antibody, clone C - 50 (Cat # MAB0853) . Lane 3 : Immunostaining with Isotype mouse IgG1 control.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 3852
  • Gene Name:
  • KRT5
  • Gene Alias:
  • CK5,DDD,EBS2,K5,KRT5A
  • Gene Description:
  • keratin 5
  • Gene Summary:
  • The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
  • Other Designations:
  • 58 kda cytokeratin,epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types,keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types),keratin, type II cytoskeletal 5
  • Gene Information
  • Entrez GeneID:
  • 3875
  • Gene Name:
  • KRT18
  • Gene Alias:
  • CYK18,K18
  • Gene Description:
  • keratin 18
  • Gene Summary:
  • KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • cell proliferation-inducing protein 46,cytokeratin 18
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