Immunoblot analysis of human plasma protein. Lane 1 : Recombinant CK-MM(CKM) protein isolated from E. coli. Lane 2 : Recombinant CK-BB(CKB) protein isolated from E. coli. Lane 3 : Recombinant CK-MB(CKB, CKM) protein isolated from E. coli. Lane 4 : Human CK-MB(CKB, CKM) protein.
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq