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Last updated: 2017/10/22
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GPX1 monoclonal antibody, clone 2A10

  • Catalog # : MAB0730
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant GPX1.
  • Immunogen:
  • Recombinant protein corresponding to full length human GPX1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunoprecipitation (1 ul)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation analysis of HL-60 cell lysates. Lane 1 : Input and lane 2 : Precipitates.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 2876
  • Gene Name:
  • GPX1
  • Gene Alias:
  • GSHPX1,MGC14399,MGC88245
  • Gene Description:
  • glutathione peroxidase 1
  • Gene Summary:
  • This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • cellular glutathione peroxidase
  • Related Disease
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