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Last updated: 2016/12/4
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GPX4 monoclonal antibody, clone 7A4

  • Catalog # : MAB0707
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant GPX4.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 25-197 of human GPX4.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunoprecipitation (1-2 ul)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2879
  • Gene Name:
  • GPX4
  • Gene Alias:
  • MCSP,PHGPx,snGPx,snPHGPx
  • Gene Description:
  • glutathione peroxidase 4 (phospholipid hydroperoxidase)
  • Gene Summary:
  • Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq
  • Other Designations:
  • glutathione peroxidase 4,phospholipid hydroperoxidase,phospholipid hydroperoxide glutathione peroxidase, mitochondrial,sperm nucleus glutathione peroxidase
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