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Last updated: 2016/11/27
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PRDX3 monoclonal antibody, clone 2B11

  • Catalog # : MAB0696
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant PRDX3.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 63-256 of human PRDX3.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Immunoprecipitation (1-2 ul)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation analysis of 293T cell lysates. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with PRDX3 monoclonal antibody, clone 2B11 (Cat # MAB0696).
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Gene Name:
  • PRDX3
  • Gene Alias:
  • AOP-1,AOP1,MER5,MGC104387,MGC24293,PRO1748,SP-22
  • Gene Description:
  • peroxiredoxin 3
  • Gene Summary:
  • This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020590,antioxidant protein 1,thioredoxin-dependent peroxide reductase
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