PAPPA monoclonal antibody, clone 7A6
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Specification
Product Description
Mouse monoclonal antibody raised against native PAPPA.
Immunogen
Native purified human PAPPA.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Sandwich ELISA
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Gene Info — PAPPA
Entrez GeneID
5069Gene Name
PAPPA
Gene Alias
ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1
Gene Description
pregnancy-associated plasma protein A, pappalysin 1
Omim ID
176385Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq
Other Designations
OTTHUMP00000022806|aspecific BCL2 ARE-binding protein 2|differentially placenta 1 expressed protein|insulin-like growth factor-dependent IGF binding protein-4 protease|pregnacy-associated plasma protein A|pregnancy-associated plasma protein A
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Interactome
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Disease
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