CPB2 monoclonal antibody
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Specification
Product Description
Mouse monoclonal antibody raised against native CPB2.
Immunogen
Native purified HumanCPB2.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes human TAFI, activated TAFI. Does not inhibit TAFI activation. It inhibits the activated TAFI.
Form
Liquid
Isotype
IgG3
Recommend Usage
Western Blot (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CPB2
Entrez GeneID
1361Gene Name
CPB2
Gene Alias
CPU, PCPB, TAFI
Gene Description
carboxypeptidase B2 (plasma)
Omim ID
603101Gene Ontology
HyperlinkGene Summary
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000018364|OTTHUMP00000018365|bA139H14.2 (carboxypeptidase B2 (plasma))|carboxypeptidase B-like protein|carboxypeptidase B2 (plasma, carboxypeptidase U)|carboxypeptidase U|plasma carboxypeptidase B2|thrombin-activable fibrinolysis inhibitor|thromb
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