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Last updated: 2017/7/23
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TLR5 monoclonal antibody, clone 19D759.2

  • Catalog # : MAB0109
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of TLR5.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 700-800 of human TLR5.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of TLR5 in A) Ramos and B) Raw cell lysate using TLR5 monoclonal antibody, clone 19D759.2 (Cat # MAB0109) at 2 ug/mL .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of TLR5 in formalin-fixed, paraffin-embedded mouse brain tissue using an isotype control (top) and TLR5 monoclonal antibody, clone 19D759.2 (Cat # MAB0109) (bottom) at 5 ug/mL .
  • Flow Cytometry
  • Flow Cytometry
  • Intracellular flow analysis of TLR5 in Ramos cells. Using 1 ug of TLR5 monoclonal antibody, clone 19D759.2 (Cat # MAB0109). Shaded histogram represents cells without antibody; Green represents isotype control (BD Biosciences) ; orange represents TLR5 (Cat # MAB0109) antibody. Secondary antibody Goat Anti-Mouse IgG PE.
  • Flow Cytometry
  • Flow Cytometry
  • Intracellular flow analysis of TLR5 in human PBMC (monocytes) using 0.5 ug of TLR5 monoclonal antibody, clone 19D759.2 (Cat # MAB0109). Shaded histogram represents cells without antibody; Green represents isotype control (BD Biosciences) ; red represents TLR5 (Cat # MAB0109). Secondary antibody Goat Anti-Mouse IgG PE.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7100
  • Gene Name:
  • TLR5
  • Gene Alias:
  • FLJ10052,MGC126430,MGC126431,SLEB1,TIL3
  • Gene Description:
  • toll-like receptor 5
  • Gene Summary:
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000036039,Toll/interleukin-1 receptor-like protein 3
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