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Last updated: 2017/2/19
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ANTXR1 monoclonal antibody, clone 200C1339(SB20)

  • Catalog # : MAB0108
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of ANTXR1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 481-497 of human ANTXR1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G chromatography
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot detection of TEM8 in TEM8 transfected 293 cell lysate. Using ANTXR1 monoclonal antibody, clone 200C1339 (SB20) (Cat # MAB0108) at 1 ug/mL .
  • Immunohistochemistry
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Gene Name:
  • ANTXR1
  • Gene Alias:
  • ATR,FLJ10601,FLJ11298,FLJ21776,TEM8
  • Gene Description:
  • anthrax toxin receptor 1
  • Gene Summary:
  • This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq
  • Other Designations:
  • 2310008J16Rik,2810405N18Rik,tumor endothelial marker 8
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