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Last updated: 2016/12/4
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TLR8 monoclonal antibody, clone 44C143

  • Catalog # : MAB0089
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of TLR8.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 750-850 of human TLR8.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 2.
  • CD molecules 2006--human cell differentiation molecules.
    Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, Boumsell L, D Buckley C, Buhring HJ, Clark G, Engel P, Fox D, Jin BQ, Macardle PJ, Malavasi F, Mason D, Stockinger H, Yang X.J Immunol Methods. 2007 Jan 30;319(1-2):1-5. Epub 2006 Dec 4.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of TLR8 in cell lysates from 293 transfected with human TLR8. Using TLR8 monoclonal antibody, clone 44C143 (Cat # MAB0089) at a concentration of 2 ug/mL .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of TLR8 in paraffin-embedded formalin-fixed human brain tissue using an isotype control (top) and TLR8 monoclonal antibody, clone 44C143 (Cat # MAB0089) (bottom) at 5 ug/mL .
  • Flow Cytometry
  • Flow Cytometry
  • Intracellular flow analysis of TLR8 in 1x10^6 Ramos cells. Using 0.5 ug of TLR8 monoclonal antibody, clone 44C143 (Cat # MAB0089) histogram represents Ramos cells without antibody; Green represents isotype control (Sigma, Cat. No. M5284) ; red represents anti-TLR8 antibody.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • TLR8
  • Gene Alias:
  • CD288,MGC119599,MGC119600
  • Gene Description:
  • toll-like receptor 8
  • Gene Summary:
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000022930
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