TLR6 monoclonal antibody, clone 86B1153.2
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of TLR6.
Immunogen
A synthetic peptide corresponding to amino acids 408-424 of human TRL6.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of TLR6 in paraffin-embedded formalin-fixed human liver tissue using an isotype control (top) and TLR6 monoclonal antibody, clone 86B1153.2 (Cat # MAB0086) (bottom) at 5 ug/mL .Flow Cytometry
Intracellular FACS analysis of TLR6 (shaded peak) and mouse IgG1 isotype control (open peak) in 10^6 Ramos cells using 3 ugs of TLR6 monoclonal antibody, clone 86B1153.2 (Cat # MAB0086). -
Gene Info — TLR6
Entrez GeneID
10333Gene Name
TLR6
Gene Alias
CD286
Gene Description
toll-like receptor 6
Omim ID
605403Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. [provided by RefSeq
Other Designations
OTTHUMP00000158730
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Interactome
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Pathway
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Disease
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Publication Reference
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MECP2 mutations in Rett syndrome adversely affect lymphocyte growth, but do not affect imprinted gene expression in blood or brain.
Balmer D, Arredondo J, Samaco RC, LaSalle JM.
Human Genetics 2002 Apr; 110(6):545.
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MECP2 mutations in Rett syndrome adversely affect lymphocyte growth, but do not affect imprinted gene expression in blood or brain.
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