TIRAP monoclonal antibody, clone 20D1960.2.1
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of TIRAP. Using TIRAP monoclonal antibody, clone 20D1960.2.1 (Cat # MAB0073) at 1 : 1000 on 20 ugs of human spleen lysate.
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of TIRAP.
Immunogen
A synthetic peptide corresponding to human TIRAP.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgM
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TIRAP. Using TIRAP monoclonal antibody, clone 20D1960.2.1 (Cat # MAB0073) at 1 : 1000 on 20 ugs of human spleen lysate. -
Gene Info — TIRAP
Entrez GeneID
114609Gene Name
TIRAP
Gene Alias
FLJ42305, Mal, wyatt
Gene Description
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
Gene Ontology
HyperlinkGene Summary
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq
Other Designations
MyD88 adapter-like protein|OTTHUMP00000179130|OTTHUMP00000179132|TIR domain-containing adapter protein|TIR domain-containing adaptor protein|Toll-interleukin 1 receptor (TIR) domain-containing adapter protein|Toll-interleukin 1 receptor (TIR) domain-conta
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Interactome
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Pathway
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Disease
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