PGLYRP4 monoclonal antibody, clone 186C426
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of PGLYRP4.
Immunogen
A synthetic peptide corresponding to amino acids 95-110 of human PGLYRP4.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of PGLYRP4 in cell lysates from human brain. Using PGLYRP4 monoclonal antibody, clone 186C426 (Cat # MAB0070) at a dilution of 2 ug/mL . -
Gene Info — PGLYRP4
Entrez GeneID
57115Gene Name
PGLYRP4
Gene Alias
PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67
Gene Description
peptidoglycan recognition protein 4
Omim ID
608198Gene Ontology
HyperlinkGene Summary
Peptidoglycan recognition proteins, such as PGRPI-beta, are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls.[supplied by OMIM
Other Designations
OTTHUMP00000035128|peptidoglycan recognition protein I beta|peptidoglycan recognition protein-I-beta
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Disease
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Publication Reference
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Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1.
Uehara A, Fujimoto Y, Kawasaki A, Kusumoto S, Fukase K, Takada H.
Journal of Immunology 2006 Aug; 177(3):1796.
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Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via toll-like receptors, NOD1 and NOD2 in human oral epithelial cells.
Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto S, Satta Y, Sasano T, Sugawara S, Takada H.
Cellular Microbiology 2005 Feb; 7(5):675.
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Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1.
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