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Last updated: 2017/3/19
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TBK1 monoclonal antibody, clone 108A429

  • Catalog # : MAB0053
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of TBK1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 563-577 of human TBK1.
  • Sequence:
  • YYQFKKDKAERRLAYC
  • Host:
  • Mouse
  • Reactivity:
  • Bovine, Dog, Human, Mouse, Rat
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of TBK1 in (A) human Daudi cell lysate and (B) mouse RAW cell lysate using TBK1 monoclonal antibody, clone 108A429 (Cat # MAB0053) at 2 ug/mL .
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis of TBK1. Using TBK1 monoclonal antibody, clone 108A429 (Cat # MAB0053) 2 ug/mL dilution against 10 ug/lane of lysate from 293 cells transfected with human TBK1 cDNA.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • TBK1
  • Gene Alias:
  • FLJ11330,NAK,T2K
  • Gene Description:
  • TANK-binding kinase 1
  • Gene Summary:
  • The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. [provided by RefSeq
  • Other Designations:
  • NF-kB-activating kinase
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