STC-1 monoclonal antibody, clone 2D9
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Specification
Product Description
Mouse monoclonal antibody raised against stanniocalcin-1.
Immunogen
Recombinant Flag fusion protein corresponding to amino acids 84-247 of human STC1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b, kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein with Flag tag on ELISA and Western Blot. Flag tag alone is used as a negative control.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — STC1
Entrez GeneID
6781Protein Accession#
P52823Gene Name
STC1
Gene Alias
STC
Gene Description
stanniocalcin 1
Omim ID
601185Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq
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Disease
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