STC-2 monoclonal antibody, clone 4H7
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Specification
Product Description
Mouse monoclonal antibody raised against stanniocalcin-2.
Immunogen
Recombinant Flag fusion protein corresponding to amino acids 25-302 of human STC2.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1, kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein on ELISA.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — STC2
Entrez GeneID
8614Protein Accession#
O76061Gene Name
STC2
Gene Alias
STC-2, STCRP
Gene Description
stanniocalcin 2
Omim ID
603665Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq
Other Designations
STC-related protein|stanniocalcin-related protein
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Interactome
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Disease
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