Human HbA1c monoclonal antibody, clone 2H5
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Specification
Product Description
Mouse monoclonal antibody raised against glycosylated hemoglobin.
Immunogen
A peptide (conjugated with KLH) corresponding to N-terminus glycosylated HbA1c.
Host
Mouse
Reactivity
Human
Form
Liquid
Conjugation
KLH
Isotype
IgG2b, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA
Detection limit for HbA1c is approximately 1ng/ml as a capture antibody. -
Gene Info — HBA1
Entrez GeneID
3039GeneBank Accession#
NM_000558Protein Accession#
NP_000549Gene Name
HBA1
Gene Alias
HBH, HBA-T3
Gene Description
hemoglobin, alpha 1
Omim ID
141800Gene Ontology
HyperlinkGene Summary
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq
Other Designations
alpha 1 globin|alpha one globin|alpha-1 globin|alpha-1-globin|hemoglobin alpha 1 globin chain|hemoglobin alpha-1 chain
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